Professor; Director, Nuclear Magnetic Resonance Research Resource (NMR3)
Related information
Email:听jan.rainey@dal.ca
Phone:听902-494-4632
Mailing Address:
Department of Biochemistry & Molecular Biology
麻豆传媒
5850 College St., Room 9-B1
PO Box 15000
Halifax, NS B3H 4R2
Canada
听
Research Topics:
- Physical chemistry
- Biological chemistry
- Computational chemistry
- Spectroscopy
- NMR spectroscopy
- Scanning probe microscopy
- Structural biology
- Protein chemistry
- Protein engineering
Education
- BSc, University of Guelph
- MSc, University of Toronto
- PhD, University of Toronto
- PDF, University of Alberta
Research interests
Our focus is characterization and tailoring of protein structure and function in environments such as cell membranes or supramolecular assemblies. NMR and optical spectroscopy are employed alongside single molecule methods, with computational methods developed to correlate data from disparate techniques.
Selected awards and honours
- Canadian Institutes of Health Research New Investigator Award, 2012-2017
- Natural Sciences and Engineering Research Council of Canada Postdoctoral Fellowship, 2004-2006
- Alberta Heritage Foundation for Medical Research Postdoctoral Fellowship, 2003-2006
- Natural Sciences and Engineering Research Council of Canada Postgraduate Scholarship, 2000-2002
Selected publications
- 鈥淎pelin conformational and binding equilibria upon micelle interaction primarily depend on membrane-mimetic headgroup.鈥� K. Shin, M. Sarker, S.K. Huang and Jan K. Rainey* (Sci. Rep., 2017, 7: 15433)
- 鈥�Structural and mechanical roles for the C-terminal non-repetitive domain become apparent in recombinant spider aciniform silk.鈥澨�L. Xu, T. Lef猫vre,听K.E.听Orrell,听Q. Meng, M. Auger, X-Q. Liu* and Jan K. Rainey* (Biomacromolecules, 2017,听18, 3678-3686)
- 鈥淧reserved transmembrane segment topology, structure, and dynamics in disparate micellar environments.鈥� D.N. Langelaan, A. Pandey, M. Sarker and Jan K. Rainey* (J. Phys. Chem. Lett., 2017, 8, 2381-2386)
- 鈥淭racking transitions in spider wrapping silk conformation and dynamics by听19F nuclear magnetic resonance spectroscopy.鈥� M. Sarker, K.E. Orrell, L. Xu, M-L. Tremblay, J.J. Bak, X-Q. Liu and Jan K. Rainey* (Biochemistry, 2016, 55, 3048-3059.)
- 鈥淐haracterization of variant soft nanoparticle structure and morphology in solution by NMR spectroscopy. 鈥� M. Sarker, R.E. Fraser, M.D. Lumsden, D.J. Anderson and Jan K. Rainey* (J. Phys. Chem. C, 2015, 119, 7461-7471)