麻豆传媒

 

Determining risk factors for dementia

Links between general health and Alzheimer's-linked dementia

- November 1, 2011

Dr. Kenneth Rockwood. (Submitted photo)
Dr. Kenneth Rockwood. (Submitted photo)

A 麻豆传媒 study focusing on risk factors for dementia could change our overall approach to health and aging, says Dr. Kenneth Rockwood.

The Kathryn Allen Weldon Professor of Alzheimer Research applied an index of health variables 鈥攆rom abdominal pain, to denture fracture, to urinary tract infections鈥攏one of which independently had any connection to dementia, to comprehensive data from the Canadian Study on Health and Aging.

鈥淲e measured 19 variables and after people had five or more 鈥 any five 鈥 the risk of dementia increased,鈥 says Dr. Rockwood. 鈥淎nd the the risk was strong enough that it defeated all of the traditional risk factors.鈥

The 7,000 older adults in the original study, on which Rockwood also worked, had no cognitive impairment at baseline.

鈥淭he hypothesis worked out as planned but it is quite amazing to stand there and look at it play out that way,鈥 he admits.

The study was prompted chiefly by Dr. Rockwood's observations in his daily work as a Nova Scotia geriatrician.

鈥淲e don't look after people who have one thing wrong,鈥 he notes. 鈥淲e specialize in people with multiple, interacting social and medical problems. And we see that any single illness, when it takes place in people with many other things wrong, does not look a lot like that single illness when it takes place in people who don't have anything else wrong.鈥

Reconsidering medical care for seniors


The report could impact the way in which the health system approaches ill seniors.

鈥淭here's a different way to do our work when people have multiple things wrong. The traditional model assumes away many other things that people have wrong. Our model embraces it,鈥 says Dr. Rockwood.

鈥淭his doesn't have anything to do with dementia per se. It's about increasing recognition that as people get older鈥攑articularly in the 9th and 10th decades鈥攖he line between disease and age is an artificial one.鈥

But Dr. Rockwood admits he's already encountered resistance to that notion: 鈥淪ociologists hate this 鈥 they say 'You are medicalizing old age.' But the approach we have right now is focused too much on single illnesses and not on the people in whom many illnesses occur. We need to step back and look at the big picture.鈥

The next step is producing a data set in which the illness of interest is not dementia 鈥 perhaps focusing on heart disease to test the same theory.


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